Descriptions:Bone Morphogenetic Protein-7 (BMP-7) is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP7 can significantly inhibit TGF-β through binding with TGF-β receptor and trigger SMAD transcription factors, such as SMAD 1 /5/8. It plays a vital role in inhibiting the expansion of kidney damage and promoting the differentiation of osteoblasts.
Applications:His tag
Tags:BMP-7
Descriptions:Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is secreted by a number of different cell types (including activated T cells,Bcells,macrophages,mast cells,endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimulation.
Applications:His tag
Tags:M-CSF
Descriptions:M-CSF is a potent hematopoietic factor produced by a variety of cells,including lymphocytes,monocytes,fibroblasts,endothelial cells,myoblasts and osteoblasts.
Applications:His tag
Tags:M-CSF
Descriptions:Interleukin-17F(IL-17F) is a cytokine with similar sequence to IL-17.The most significant role of IL-17 is to participate in inducing and mediating pro-inflammatory reaction.
Applications:His tag
Tags:IL-17F
Descriptions:Transforming Growth Factors beta 2 (TGFβ-2) is a 12.85 kDa member of the epidermal Growth Factors with 113 amino acid residues. TGFβ-2 is expressed from throughout the body. TGFβ-2 is a regulator of cell proliferation, differentiation, apoptosis, cell plasticity and migration, etc. TGF-β-2 also associates with various kinds of diseases, such as cancer and tissue fibrosis.
Applications:His tag
Tags:TGF-β2
Descriptions:Interleukin 24 (IL-24) predicts a molecular mass of 18.2 kDa, is a cytokine belonging to the IL-10 family of cytokines that signals through IL-20R1 /IL-20R2 and IL-22R1 /IL-20R2. Its normal physiological role relates to wound healing, protection against diseases caused by bacteria.
Applications:His tag
Tags:IL-24
Descriptions:C-X-C motif chemokine 6 (CXCL6) also named granulocyte chemotactic protein 2 (GCP-2), which is a chemokine of the intercrine alpha family. CXCL6 is a 8.3kDa protein containing 75 amino acid residues. CXCL6 has a significant role in resistance of gram-positive and gram-negative bacteria which is a chemotaxis for neutrophil granulocytes. CXCL6 has a role in in the process of carcinogenesis which affects proliferation and metastasis of OS cells by the interaction with CXCR1 /CXCR2.
Applications:His tag
Tags:CXCL6
Descriptions:Interleukin 17F (IL-17F) predicts a molecular mass of 30.1 kDa, is a cytokine of innate and adaptive immune system involved in antimicrobial host defense and maintenance of tissue integrity. It is involved in the development of inflammation and host defense against infection by inducing the expression of genes that encode other proinflammatory cytokines, such as tumor necrosis factor, interleukin 1, interleukin 6 and some members of the colony-stimulating factor family.
Applications:His tag
Tags:IL-17F
Descriptions:Interleukin-1 alpha (IL1 alpha or IL1α) is a member of the interleukin-1 cytokine family, found constitutively present in epithelial layers of the entire gastrointestinal tract, lung, liver, kidney, endothelial cells, and astrocytes. The synthesized IL-1 alpha is a 31 kDa inactive precursor and can be cleaved by intracellular caspase-1 or extracellular proteases to generate the bioactive 17 kDa form and the 16 kDa N-terminal cleavage product. Both precursor and mature IL-1 alpha protein bind to the IL-1 receptor (IL-1R), initiating a cascade of inflammatory cytokines and chemokines production such as IL-6, IL-8, and TNF, in response to viral and bacterial pathogens conditions. IL-1 alpha plays a central role in immune-surveillance mechanisms, stimulating macrophages, neutrophils, and CD8+ T cells activity.
Applications:His tag
Tags:IL-1α