Observing three-dimensional dynamics of the nucleus in live cells, Abbkine will give you great experiences !
Live-cell imaging technique allows real-time examination of almost every aspect of cellular function under normal and experimental conditions, so it is especially popular with cytology researchers. Abbkine TraKine™ Pro is a series of cell-permeable organic fluorescent probes which can selectively recognize and label organelles. Currently, we launched the staining kits involve tubulin, lysosome, mitochondrion and nuclei. This paper introduces the TraKine™ Pro Live-cell Nuclei Staining kit (Deep Red Fluorescence with Super Resolution). Function of nucleus The nucleus is the largest and most important cell structure in eukaryotic cells, mainly composed of nuclear envelope, chromatin, nuclear skeleton, nucleolus and nucleosome. Nuclear membrane is a two-layer membrane that completely encloses the nucleus and separates the material within the membrane from the cytoplasm…
Caspase(1,2,3,4,6,8,9) Assay Kit- Simple and convenient, to boost your apoptosis study
【Tips】If you are studying whether a certain drug can trigger apoptosis which relys on the caspase related pathway, and want to detect the activity of caspase, this article is suitable for you! This article is especially fit for researchers who are working hard to benefit the mankind. 【Background】 Caspases(cysteine-aspartic proteases) are a family of protease enzymes playing essential roles in programmed cell death (including apoptosis, pyroptosis and necroptosis) and inflammation. The cascade reaction caused by caspases is a central part of the apoptotic process, and its activation mainly includes the mitochondria-dependent pathway and the death receptor-mediated signal transduction pathway. The downstream caspases are then activated, leading to apoptosis by cleavage of specific substrates. Inhibition of apoptotic function will lead to…
Abbkine newly released Selected Primary Antibody will shock you！
Abbkine strongly launched selected primary antibody with high quality control, which will be your reliable choice. The selected primary antibody involves most of the hot target research areas, and through multiple rigorous quality controls, to meet your high-quality requirements. Thanks for the trust and support from all the new and old customers, Abbkine now launches new products one-stop promotion, matching the top selling products, buy one get one! With bulk stock, the product can be sent immediately after payment. Promotion Details are as follows: Promotion time: From now to December 31th, 2019 Contents: Selected Primary Antibody one-stop matching service, buy one get one! (involve the hot target areas such as Apoptosis, Signal Transduction, Neuroscience, and so…
TraKine™ Pro Mitochondrion live-cell Fluorescence Probe-I just want to surpass MitoTracker®！
【REVIEW】： TraKine™ Pro Live-cell Fluorescence Tool-Perfect compatibility with long-term super-resolution fluorescence imaging TraKine™ Pro Live-cell Tubulin Staining kit-Your Best Choice for Cytoskeleton Study Living cell staining, super-resolution Lysosome tracing Extensive research has indicated that intracellular organelles are integrated into cellular networks and collaborate on various cellular tasks rather than acting as isolated entities. Specialized membrane contact sites are formed between organelles, providing distinct spatial regions for executing and regulating their functions. Mitochondria is crucial dynamic organelles that participate extensively in many important cellular processes. Its dysfunction has been implicated in diverse diseases such as neurodegenerative disorders, cancer, and cardiovascular diseases. Capturing the dynamic process of subcellular organelles in living cells is crucial to the study of disease mechanism. The limitations…
Living cell staining, super-resolution Lysosome tracing
【REVIEW】： TraKine™ Pro Live-cell Fluorescence Tool-Perfect compatibility with long-term super-resolution fluorescence imaging TraKine™ Pro Live-cell Tubulin Staining kit-Your Best Choice for Cytoskeleton Study Lysosome is an important organelle in animal cells. Its integrity is closely related to animal physiology and pathology. Lysosomes are vesicle-like organelles surrounded by a single membrane and containing a variety of acidic hydrolases. Their main function is to carry out intracellular digestion and specialize in decomposing various exogenous and endogenous macromolecular substances. Lysosomes in cells are heterogeneous, and the size and types of hydrolytic enzymes contained in lysosomes may vary greatly. The marker enzyme is acid phosphatase. Recent studies have found that phagocytes and lysosomes have bidirectional signaling functions. The ability of lysosomes to move towards…
TraKine™ Pro Live-cell Tubulin Staining kit-Your Best Choice for Cytoskeleton Study
【Review 】 TraKine™ Pro Live-cell Fluorescence Tool-Perfect compatibility with long-term super-resolution fluorescence imaging As soon as the Abbkine TraKine™ Pro fluorescent dyes were released, they received high attention from living cell imaging researchers all over the world. With extremely high specificity, the probes can last for several hours in living cells, which is particularly suitable for studying the dynamics and interactions of subcellular structures in live cells for super-resolution imaging. In eukaryotes, microtubules are one of the main components of cytoskeleton. Cytoskeleton is not only involved in supporting cells, but also related to almost all forms of cell movements, such as cell migration, transport of organelles and macromolecules. In addition, it is closely related to signal transduction and cell division.…
TraKine™ Pro Live-cell Fluorescence Tool-Perfect compatibility with long-term super-resolution fluorescence imaging
Combining genetic marker method with small and bright probes that can be controlled by light-controlled switches will be a very ideal method to develop molecular-level ultra-high resolution imaging in the future. - Xiaowei Zhuang (Discoveries of novel cellular structures using STORM) Inspired by academician Xiaowei Zhuang, Abbkine TraKine™ Pro series of fluorescent dyes came into being. TraKine™ Pro is series of long-term super-resolution cell staining imaging portfolio for labeling subcellular structures of live and fixed cells. TraKine™ Pro proprietary excellent fluorescent dyes span the full UV-visible and near IR spectrum. This release of the TraKine™ Pro series featured hot research targets, including, Tubulin: One of the important components of eukaryotic cytoskeleton, plays an important role in maintaining cell morphology, cell…
Just choose Abbkine products for your interleukin study
What’s interleukin? What important roles do they play ? Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that were first seen to be expressed by white blood cells (leukocytes), The name "interleukin" was chosen in 1979, during the Second International Lymphokine Workshop in Switzerland. An Arabic number is added after the name to distinguish them, such as IL-1, IL-2..., the newly determined factors are named in turn. Interleukin is a kind of cytokines secreted by macrophages, lymphocytes and other cells. Its main biological functions involve the participation in immune response and immune regulation, constitution of the molecular systems that transmit signals between cells, and so on. Different interleukins have different sources and functions, and…
Abbkine was invited to exhibit at American Association for Cancer Research (AACR) 2019, Atlanta, Georgia
Abbkine invites you to visit AACR 2019, Atlanta, Georgia! Abbkine latest products and services will be displayed at the exhibition. There always be one type can flash into your eyes. American Association for Cancer Research (AACR) 2019 Date: March 31 to April 3, 2019 Booth: #4454 Address: Georgia World Congress Center in Atlanta, Georgia About: The AACR Annual Meeting program covers the latest discoveries across the spectrum of cancer research—from population science and prevention; to cancer biology, translational, and clinical studies; to survivorship and advocacy—and highlights the work of the best minds in research and medicine from institutions all over the world. Welcome to visit our booth #4454.
Happy Chinese Lunar New Year of Pig
Dear customers, We would like to take this opportunity to thank you for your kind support all the time. Please kindly be advised that our company will be closed from January 30, 2019 to February 11, 2019, in observance of the Chinese traditional festival, Spring Festival. Hence our office and warehouse are closed during the above period. Please feel free to contact us by sending E-mail to service@abbkine.com. Orders will be accepted but not be processed until February 12, 2019, the first business day after the Spring Festival. Sorry for any inconvenience caused. Happy New Year to you and your family! Abbkine Scientific Co., Ltd. About Abbkine Scientific Co., Ltd. Abbkine serves global scientists in the field of Proteomics and Cytology,…
