Descriptions：Sucrase
Tags：Sucrase
Descriptions：Mouse IFN alpha 1a Protein, His tag (Animal-Free), expressed in E. coli
Applications：His tag
Tags：IFN-α1a
Descriptions：Bone morphogenetic protein -4 (BMP-4) is one of nine structurally related BMP's, belonging to transforming growth factor-β (TGF-β) superfamily, which secretes proteins. Mature BMP-4 is a dimer that binds to a multimeric transmembrane receptor with serine/threonine kinase activity. BMP-4 treatment promoted the proliferation of HCC cells and induced autophagy. Mechanism study shows that autophagy induced by BMP-4 is mediated by activating JNK1/Bcl2 pathway. JNK1 inhibitor and JNK1 knockout can weaken BMP-4-induced autophagy and eliminate BMP-4-promoted HCC cell growth. BMP-4 promotes the proliferation of HCC through autophagy activation of JNK1/Bcl-2 signaling.
Applications：No tag
Tags：BMP-4
Descriptions：Methylcitrate Synthase (MCS)
Descriptions：Human CD40L (CD154) is one member of TNF family which is expressed on T cells. It binds the CD40, which is on the antigen-presenting cells (ex: B cells, macrophages and monocytes) Human CD40L is a 21.6 kDa cytokine with 103 amino acid residues which is a transmembrane glycoprotein. Human CD40L plays an important role in the adaptive immune system which induces the B cell maturation and activation.
Applications：His tag
Tags：CD40L
Descriptions：4-1BB ligand (4-1BBL) is a type II transmembrane protein that is part of the tumor necrosis factor (TNF) ligand family. As an inducible co-stimulatory molecule, it presents on several antigen presenting cell (APC) types, including B cells, macrophages and DCs. The interactions between 4-1BB and 4-1BBL trigger pleiotropic effects on the immune response including antigen presenting process, proliferation of CD4 and CD8 positive T-cells, as well as cytokine secretion from T-cells through NFκB, c-Jun, and p38 downstream signal pathways activation.Therefore, 4-1BB and 4-1BBL are recently used for the immunotherapy of cancer.
Applications：His tag
Tags：4-1BBL
Descriptions：Trehalose
Tags：Trehalose
Descriptions：Cholera toxin (CT) is an AB5 enterotoxin produced by Vibrio cholerae and is responsible for the disease manifestations. Several publications indicate that the toxin binds to glycoprotein and that the B-chain binds to GM1 ganglioside pentasaccharide on the cell surface.
Applications：No tag
Tags：Toxin B
Descriptions：EliKine™ Human Alpha Fetoprotein (AFP) ELISA Kit employs a two-site sandwich ELISA to quantitate Human AFP.
Reactivity：Human
Applications：ELISA
Tags：AFP
Descriptions：FDP
Tags：FDP
