Descriptions:R-spondin 1 (RSPO1, Roof plate-specific Spondin 1) is a cysteine-rich secreted glycoprotein that belongs to the R-Spondin family. Structurally, R-spondin 1 harbors an N-terminal signal peptide, two cysteine-rich furin-like (FU1-FU2) domains, a thrombospondin (TSP) domain, and a basic amino acid-rich (BR) C-terminal domain. R-spondin 1 acts as a ligand for the leucine-rich repeat-containing G-protein coupled receptor (LGR) family (LGR4/5/6), subsequent clearing negative regulators ZNRF3/RNF43 from the membrane, leading to the availability of Wnt receptor and activating Wnt/β-catenin signaling. The signal cascade is essential for regulating stem cell proliferation, embryonic development, and tissue homeostasis.
Applications:His-SUMO tag
Tags:RSPO1/R-spondin 1
Descriptions:核因子κB受体激活(RANK)配体(RANKL)是TNF细胞因子超家族中的镰基分裂,具有外结构域的II型跨膜蛋白。RANKL是一个核苷酸为19.8 kDa的蛋白质,含有3317个残基,在T细胞和显着T细胞的器官(如表达胸腺和肝脏)中高。RANKL-RANK(RANKL受体)在骨代谢、胶原蛋白和免疫系统中发挥重要作用。
Tags:RANKL
Descriptions:Human IL-23 p19 Protein, His tag (Animal-Free), expressed in E. coli
Tags:IL-23 p19
Descriptions:Interleukin 36 receptor antagonist (IL-36RA) is a 16.97 kDa member of IL-1 family with 155 amino acid residues. IL-1RA is expressed by lymphoid tissue, skin and secreted to blood. IL-36Ra functions as a receptor antagonist that inhibits the activation of IL-36R signaling and suppresses pro-inflammatory signaling.
Applications:His tag
Tags:IL-36RA
Descriptions:EliKine™ Mouse GLP-1 Competitive ELISA Kit uses a competitive method to quantify mouse GLP-1 in a sample.
Reactivity:Mouse
Applications:ELISA
Tags:No-tag
Descriptions:This Rat Transient receptor potential cation channel subfamily M member 7 (TRPM7) ELISA Kit employs a two-site sandwich ELISA to quantitate TRPM7.
Reactivity:Rat
Applications:ELISA
Tags:TRPM7
Descriptions:Rat Anti-Mullerian hormone (AMH) ELISA Kit employs a two-site sandwich ELISA to quantitate AMH in samples.
Reactivity:Rat
Applications:ELISA
Tags:AMH
Descriptions:This Human Urotensin 2 (UTS2) ELISA Kit employs a two-site sandwich ELISA to quantitate UTS2.
Reactivity:Human
Applications:ELISA
Tags:UTS2
Descriptions:This Human CUGBP Elav-like family member 3 (TNRC4) ELISA Kit employs a two-site sandwich ELISA to quantitate TNRC4.
Reactivity:Human
Applications:ELISA
Tags:TNRC4
Descriptions:This Rat Tenomodulin (TNMD) ELISA Kit employs a two-site sandwich ELISA to quantitate TNMD.
Reactivity:Rat
Applications:ELISA
Tags:TNMD