Descriptions:Interleukin 30 (IL-30) forms one chain of the heterodimeric cytokine called interleukin 27 (IL-27), thus it is also called IL27 p28, it predicts a molecular mass of 24.9 kDa. IL-30, the p28 subunit that forms IL-27 together with EBI3 and is also known as IL-27 p28 or IL-27A, has been considered a surrogate to represent IL-27. It was initially thought to be an IL-12-like cytokine promoting Th1 immunity because of its ability to induce T-bet and IL-12Rβ2 expression through STAT1 activation during Th1 differentiation.
Tags:IL-30
Descriptions:抑瘤素M (OSM)是一种糖蛋白,属于白细胞介素-6 (IL-6)细胞因子家族,该家族包括循环抑制因子、细胞集落刺激因子和白细胞介素-6。OSM是一种编码生长调节因子,可抑制多种肿瘤细胞系的增殖。它刺激AIDS-KS颗粒细胞的增殖。OSM调节细胞因子的产生,包括内皮细胞产生的IL-6、G-CSF和GM-CSF。OSM被许多认为是一种多效性细胞因子,通过特定的细胞表面摄取启动其生物活性。低亲和力含有gp130的蛋白质相似,现已被鉴定为高亲和力OSM受体的组成部分,可传递OSM信号。OSM还被证明在促炎和抗炎作用中发挥作用。OSM可能参与生物过程,包括胚胎发育、造血、通道重建、形成和破坏以及可能的中枢系统发育。
Tags:OSM
Descriptions:Human IL-8 (72 a.a.) Protein, His tag (Animal-Free), expressed in E. coli
Tags:IL-8
Descriptions:Interleukin 36 gamma (IL-36 gamma) is a 17.65 kDa cytokine with 159 amino acid residues. IL-36 gamma is a member of the IL-1 family and is mainly expressed in keratinocytes, bronchial epithelial cells, macrophages, and monocyte. This cytokine responds to multiple pathogen-associated molecular patterns (PAMPs) and participates in the inflammatory response. In addition, it also induces the production of pro-inflammatory cytokines like IL-12, IL-1β, IL-6, TNF-α, and IL-23.
Applications:His tag
Tags:IL-36γ
Descriptions:巨噬细胞集落刺激因子 (M-CSF) 是一种分子量为 19.02 kDa 的造血生长因子,含有 162 个氨基酸残基。该蛋白的活性形式为同型二聚体,由成骨细胞分泌。M-CSF 调控单核细胞、巨噬细胞和骨髓祖细胞的产生、分化和功能。M-CSF 能够通过与其受体 CSF-1R 结合来激活 CSF-1 信号通路。
Tags:M-CSF
Descriptions:Human SCF Protein, His tag (Animal-Free), expressed in E. coli
Tags:SCF
Descriptions:This Rat Tenascin-R (TNR) ELISA Kit employs a two-site sandwich ELISA to quantitate TNR.
Reactivity:Rat
Applications:ELISA
Tags:TNR
Descriptions:This Human Nuclease-sensitive element-binding protein 1 (YBX1) ELISA Kit employs a two-site sandwich ELISA to quantitate YBX1.
Reactivity:Human
Applications:ELISA
Tags:YBX1