Descriptions:Interleukin 16(IL-16) predicts a molecular mass of 13.5 kDa, encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication, and signaling process of this cytokine is mediated by CD4.
Applications:His tag
Tags:IL-16
Descriptions:GPb
Tags:GPb
Descriptions:Interleukin-1 beta (IL-1β) is a major cytokine expressed in macrophage, NK cells, monocytes, and neutrophils. It also plays fundamental role in inflammatory response, including monocyte activation, which is essential for the host defense and pathogen and pathogen resistance. Pro-IL-1β is cleaved by cytosolic caspase 1 to form mature IL-1β.
Applications:His tag
Tags:IL-1β
Descriptions:Interleukin 30 (IL-30) forms one chain of the heterodimeric cytokine called interleukin 27 (IL-27), thus it is also called IL27 p28, it predicts a molecular mass of 24.9 kDa. IL-30, the p28 subunit that forms IL-27 together with EBI3 and is also known as IL-27 p28 or IL-27A, has been considered a surrogate to represent IL-27. It was initially thought to be an IL-12-like cytokine promoting Th1 immunity because of its ability to induce T-bet and IL-12Rβ2 expression through STAT1 activation during Th1 differentiation.
Applications:His tag
Tags:IL-30
Descriptions:Insulin Like Growth Factors 1 (IGF-I) is a 7.81 kDa member of the Insulin-like Growth Factors with 71 amino acid residues. IGF-I is mainly expressed from liver, adipose tissue, cervi, endometrial stromal cells, leydig cells, and can be isolated from plasma. IGF-I is mediating the protein anabolic and promoting effect of pituitary growth hormone. IGF-I also affects metabolism of glycogen, DNA synthesis and glucose uptake via binding to IGF-I receptor.
Applications:His tag
Tags:IGF-I
Descriptions:Sucrase
Tags:Sucrase
Descriptions:Interleukin 20 (IL-20) predicts a molecular mass of 17.6 kDa. The IL-20 subfamily of cytokines is comprised of IL-19, IL-20, IL-22, IL-24, and IL-26. It regulates of differentiation of keratinocytes during inflammation, the expansion of multipotential hematopoietic progenitor cells.
Applications:His tag
Tags:IL-20
Descriptions:Tumor Necrosis Factor Beta (TNF beta) or lymphotoxin-alpha (LT-α) is a 19 kDa tumor necrosis factor family protein with 171 amino acid residues. TNF beta is mainly expressed from lymphocytes, and mediates variety of inflammatory, immunostimulatory, and antiviral responses. TNF beta also involves development in secondary lymphoid organs. It is cytotoxic for different tumor cells in vitro and in vivo.
Applications:His tag
Tags:TNF beta
Descriptions:Interleukin 17A (IL-17A) predicts a molecular mass of 35 kDa, encoded IL17A gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappa B and mitogen-activated protein kinases.
Applications:His tag
Tags:IL-17
Descriptions:Galectin-8 (Gal-8) is a lectin family member and is one of the tandem repeat-type galectins containing two carbohydrate recognition domains (CRD) connected by a linker region in a single peptide chain. The CRD is responsible for β-galactoside binding, and the binding partners for galectin-8 have been identified, including CD44 and a subset of integrins. Galectin-8 and integrins form complexes, subsequently leading to phosphorylation of paxillin and focal adhesion kinase (FAK), which activates signal pathways including MAPK-ERK and PI3K-AKT pathways. Galectin-8 is constitutively presented in the Liver, kidney, cardiac muscle, lung, and brain. Galectin-8 serves as an immunosuppressive protective role against autoimmune CNS inflammation, regulating the balance of Th17 and Th1 polarization.
Applications:His tag
Tags:Galectin-8