Descriptions:Granulocyte Colony-Stimulating Factor (G-CSF) is a 18.67 kDa protein containing 207 amino acid which secreted by monocytes, macrophages, fibroblasts, and endothelial cells, regulates cell growth, maturation, and development of myeloid cells. G-CSF is a member of the CSF family of glycoproteins, and makes the bone marrow produce more white blood cells so it can reduce the risk of infection after some types of cancer treatment. G-CSF is also an established useful clinical agent for increasing neutrophilic granulocytes levels. Mouse G-CSF shares 73% sequence homology with human G-CSF.
Tags:G-CSF
Descriptions:人白细胞介素 4 (IL-4) 是一种在调节炎症和免疫 反应中发挥重要作用的细胞因子。它诱导 T 细胞分化为 Th2 细胞。该细胞因子与 IL-4 受体结合,而该受体也与另一种细胞因子白细胞介素 13 (IL-13) 结合,这或许可以解释 IL-4 和 IL-13 功能的重叠。
Tags:IL-4
Descriptions:Interleukin 29 (IL-29) is a cytokine, predicts a molecular mass of 21.9 kDa. It belongs to type III interferons group, also termed interferons λ (IFN-λ). Its induction of STAT3-STAT5 has also been displayed, albeit to a lesser degree. The STAT1 /STAT2 signaling cascade transpires as follows: once tyrosine residues on STAT1 and STAT2 are phosphorylated, these proteins dimerize and are subsequently transported to the nucleus.
Tags:IL-29
Descriptions:Human IL-23 p19 Protein, His tag (Animal-Free), expressed in E. coli
Tags:IL-23 p19
Descriptions:血管内皮生长因子165 (VEGF165)是一种强效的生长和血管生成细胞因子,属于VEGF家族,包括VEGF-A、VEGF-B、VEGF-C、VEGF-D、VEGF-E和PIGF。VEGF165是一种丰富的糖基化细胞因子,由缺少相同的165个血管链组成。
Tags:VEGF165
Descriptions:Interleukin-1 alpha (IL1 alpha or IL1α) is a member of the interleukin-1 cytokine family, found constitutively present in epithelial layers of the entire gastrointestinal tract, lung, liver, kidney, endothelial cells, and astrocytes. The synthesized IL-1 alpha is a 31 kDa inactive precursor and can be cleaved by intracellular caspase-1 or extracellular proteases to generate the bioactive 17 kDa form and the 16 kDa N-terminal cleavage product. Both precursor and mature IL-1 alpha protein bind to the IL-1 receptor (IL-1R), initiating a cascade of inflammatory cytokines and chemokines production such as IL-6, IL-8, and TNF, in response to viral and bacterial pathogens conditions. IL-1 alpha plays a central role in immune-surveillance mechanisms, stimulating macrophages, neutrophils, and CD8+ T cells activity.
Applications:His tag
Tags:IL-1α
Descriptions:C-X-C motif chemokine 5 (CXCL5) also named epithelial-derived neutrophil-activating peptide 78 (ENA-78), which is a chemokine of the intercrine alpha family. CXCL5 is a 8kDa protein containing 70 amino acid residues. CXCL5 is stimulated by the IL-1 or TNFα during inflammation which produced by the eosinophils and CXCL5 is inhibited by the IFNγ. CXCL5 promotes the formation of blood vessels and angiogenesis by binding the cell receptor CXCR2.
Tags:CXCL5
Descriptions:H2O2
Tags:H2O2
Descriptions:Acetokinase (ACK)
Tags:Acetokinase (ACK)
Descriptions:UGP
Tags:UGP