Descriptions：4-1BB ligand (4-1BBL) is a type II transmembrane protein that is part of the tumor necrosis factor (TNF) ligand family. As an inducible co-stimulatory molecule, it presents on several antigen presenting cell (APC) types, including B cells, macrophages and DCs. The interactions between 4-1BB and 4-1BBL trigger pleiotropic effects on the immune response including antigen presenting process, proliferation of CD4 and CD8 positive T-cells, as well as cytokine secretion from T-cells through NFκB, c-Jun, and p38 downstream signal pathways activation.Therefore, 4-1BB and 4-1BBL are recently used for the immunotherapy of cancer.

Applications：His tag

Tags：4-1BBL

Descriptions：人白细胞介素 4 (IL-4) 是一种在调节炎症和免疫 反应中发挥重要作用的细胞因子。它诱导 T 细胞分化为 Th2 细胞。该细胞因子与 IL-4 受体结合，而该受体也与另一种细胞因子白细胞介素 13 (IL-13) 结合，这或许可以解释 IL-4 和 IL-13 功能的重叠。

Tags：IL-4

Descriptions：Interleukin 29 (IL-29) is a cytokine, predicts a molecular mass of 21.9 kDa. It belongs to type III interferons group, also termed interferons λ (IFN-λ). Its induction of STAT3-STAT5 has also been displayed, albeit to a lesser degree. The STAT1 /STAT2 signaling cascade transpires as follows: once tyrosine residues on STAT1 and STAT2 are phosphorylated, these proteins dimerize and are subsequently transported to the nucleus.

Tags：IL-29

Descriptions：血管内皮生长因子165 (VEGF165)是一种强效的生长和血管生成细胞因子，属于VEGF家族，包括VEGF-A、VEGF-B、VEGF-C、VEGF-D、VEGF-E和PIGF。VEGF165是一种丰富的糖基化细胞因子，由缺少相同的165个血管链组成。

Tags：VEGF165

Descriptions：Interleukin-1 alpha (IL1 alpha or IL1α) is a member of the interleukin-1 cytokine family, found constitutively present in epithelial layers of the entire gastrointestinal tract, lung, liver, kidney, endothelial cells, and astrocytes. The synthesized IL-1 alpha is a 31 kDa inactive precursor and can be cleaved by intracellular caspase-1 or extracellular proteases to generate the bioactive 17 kDa form and the 16 kDa N-terminal cleavage product. Both precursor and mature IL-1 alpha protein bind to the IL-1 receptor (IL-1R), initiating a cascade of inflammatory cytokines and chemokines production such as IL-6, IL-8, and TNF, in response to viral and bacterial pathogens conditions. IL-1 alpha plays a central role in immune-surveillance mechanisms, stimulating macrophages, neutrophils, and CD8+ T cells activity.

Applications：His tag

Tags：IL-1α

Descriptions：H2O2

Tags：H2O2

Descriptions：Acetokinase (ACK)

Tags：Acetokinase (ACK)

Descriptions：UGP

Tags：UGP

Descriptions：Interleukin 24 (IL-24) predicts a molecular mass of 18.2 kDa, is a cytokine belonging to the IL-10 family of cytokines that signals through IL-20R1 /IL-20R2 and IL-22R1 /IL-20R2. Its normal physiological role relates to wound healing, protection against diseases caused by bacteria.

Tags：IL-24

Descriptions：Human IL-23 p19 Protein, His tag (Animal-Free), expressed in E. coli

Tags：IL-23 p19