Descriptions:NAD-ME
Tags:NAD-ME
Descriptions:霍乱毒素 (CT) 是由霍乱弧菌产生的 AB5 型肠毒素,是霍乱症状的致病原因。一些文献表明,该毒素与糖蛋白结合,其 B 链与细胞表面的 GM1 神经节苷脂五糖结合。
Tags:Toxin B
Descriptions:NADP phosphatase (NADPase) is mainly present in plant tissues and is the only enzyme in organisms that catalyzes the degradation of NADP+ to NAD+. Together with NADK, it regulates the balance between NAD and NADP.
Descriptions:CAT
Tags:CAT
Descriptions:Total Polysaccharide
Tags:Total Polysaccharide
Descriptions:Fms相关酪氨酸蛋白酶3配体(Flt-3配体)是由人类FLT3LG基因编码的蛋白质。作为造血的重要调节因子,Flt-3配体酪氨酸蛋白酶具有活性,可刺激淋巴系和髓系造血祖细胞的增殖。Flt-3配体可与其他细胞因子(如GM-CSF、G-CSF、IL-3、EPO、IL-11、IL-12、IL-6或TPO)很好地促进未成熟造血祖细胞的增殖。Flt-3配体在多种造血祖细胞中表达,包括未成熟造血祖细胞和骨髓造血祖细胞。
Tags:Flt-3 Ligand
Descriptions:Interleukin-6(IL-6) is encoded by the IL-6 gene and acts as both a pro-inflammatory and anti-inflammatory cytokine.It is secreted by T cells and macrophages to stimulate immune response.
Applications:No tag
Tags:IL-6
Descriptions:DPPH
Tags:DPPH
Descriptions:GDF-3(以前称为Vgr-2)是TGF-β超家族成员,属于生长/分化因子家族。GDF-3在未分化的胚胎干细胞(ES细胞)、白色脂肪组织和脑中表达。小鼠GDF-3由366个氨基酸组成,包含一个22个氨基酸的信号序列、一个230个氨基酸的前肽和一个114个氨基酸的成熟蛋白,该成熟蛋白含有一个潜在的N-糖基化位点。成熟区包含一个在家族成员中保守的半胱氨酸结结构。然而,它缺少负责形成分子间二硫键的第四个半胱氨酸,因此GDF-3可能以非共价同型二聚体的形式存在。成熟的人GDF-3与小鼠和大鼠GDF-3的氨基酸序列同一性分别为83%和83%。大部分GDF-3以未裂解的前原形式存在。未分裂形式和成熟形式似乎均具有活性,但活性可能有所不同。所有形式均可对抗BMP。在ES细胞中,GDF-3抑制BMP2信号传导可维持多能性。GDF-3还影响早期细胞命运决定;例如,删除小鼠GDF-3会导致原肠胚形成前胚胎的前内脏内胚层出现缺陷。GDF-3在胚胎发生过程中与GDF-1协同作用,成熟蛋白具有类似节点的活性。虽然GDF家族成员通过BMP受体(ALK1、2、3和6)发出信号,从而激活Smads 1、5和8,但也有报道称GDF-3通过ALK4和ALK7发出信号,从而激活Smads 2和3。在脂肪细胞中,高脂饮食会诱导GDF-3,从而促进脂肪生成和肥胖。
Tags:GDF3
Descriptions:Transforming Growth Factors beta 2 (TGFβ-2) is a 12.85 kDa member of the epidermal Growth Factors with 113 amino acid residues. TGFβ-2 is expressed from throughout the body. TGFβ-2 is a regulator of cell proliferation, differentiation, apoptosis, cell plasticity and migration, etc. TGF-β-2 also associates with various kinds of diseases, such as cancer and tissue fibrosis.
Applications:His tag
Tags:TGF-β2