Descriptions:Glucose
Tags:Glucose
Descriptions:ICDHc
Tags:ICDHc
Descriptions:Protein S100-A9, also known as S100 calcium binding protein A9, S100A9, and CAGB, is a member of the S-100 family. S100A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi.
Tags:S100A9
Descriptions:CC基序趋化因子配体2 (CCL2) 是一个分子量为13.88 kDa的细胞因子,由125个氨基酸残基组成,又称单核细胞趋化蛋白1 (MCP1)。CCL2主要由单核细胞、巨噬细胞和树突状细胞分泌。它调节多种生物学功能,例如单核细胞、记忆T细胞、嗜酸性粒细胞和树突状细胞的募集,辅助性T细胞的外渗,对TNFα和IFNγ的应答,以及血管生成。此外,CCL2与CCR4结合后,可启动炎症反应中的白细胞迁移。
Tags:CCL2
Descriptions:β-神经生长因子 (Beta-NGF) 是一种分子量为 27 kDa 的细胞因子,含有 241 个氨基酸残基。Beta-NGF 属于神经营养因子家族,具有神经营养因子的功能。它由 α、β、γ 亚基组成,其中 β 亚基与其生物活性相关。Beta-NGF 与 p75 神经营养因子受体和 Trk 受体结合,其功能分别与细胞死亡和存活相关。
Tags:β-NGF
Descriptions:SP
Tags:SP
Descriptions:BAFF also known as BLYS, TALL-1 and TNFSF13B, which belongs to tumor necrosis factor family. BAFF is a 31.2 kDa type II transmembrane protein containing 285 residues that predominantly produced by myeloid cells, furthermore mouse BAFF shares 72% sequence identity with human BAFF. BAFF has been demonstrated to activate the survival of B cells and the B cell response by binding to BAFFR/BR3. Additionally, BAFF also takes part in regulating B and T cell function via forming two ligands-two receptors pathway through sharing TNFRSF13B/TACI and TNFRSF17/BCMA receptors with APRIL.
Tags:BAFF
Descriptions:M-CSF is a potent hematopoietic factor produced by a variety of cells,including lymphocytes,monocytes,fibroblasts,endothelialcells,myoblasts and osteoblasts.
Applications:No tag
Tags:GM-CSF
Descriptions:Fms相关酪氨酸肽3配体(Flt-3配体)是由小鼠Flt3lg基因编码的蛋白质。Flt-3配体作为造血的重要调节因子,酪氨酸肽3配体有活性,可刺激淋巴系和髓系造血祖细胞的增殖。Flt-3配体可配合使用他的细胞因子(如GM-CSF、G-CSF、IL-3、EPO、IL-11、IL-12、IL-6或TPO)很好地促进未成熟造血细胞的增殖。Flt-3配体在多种造血祖细胞中表达,包括未成熟造血细胞和骨髓基质细胞。
Tags:Flt-3 Ligand
Descriptions:霍乱毒素 (CT) 是由霍乱弧菌产生的 AB5 型肠毒素,是霍乱症状的致病原因。一些文献表明,该毒素与糖蛋白结合,其 B 链与细胞表面的 GM1 神经节苷脂五糖结合。
Tags:Toxin B