Descriptions：CC基序趋化因子配体2 (CCL2) 是一个分子量为13.88 kDa的细胞因子，由125个氨基酸残基组成，又称单核细胞趋化蛋白1 (MCP1)。CCL2主要由单核细胞、巨噬细胞和树突状细胞分泌。它调节多种生物学功能，例如单核细胞、记忆T细胞、嗜酸性粒细胞和树突状细胞的募集，辅助性T细胞的外渗，对TNFα和IFNγ的应答，以及血管生成。此外，CCL2与CCR4结合后，可启动炎症反应中的白细胞迁移。
Tags：CCL2
Descriptions：白细胞介素-10 (IL-10)，细胞因子合成抑制细胞因子(CSIF)，是一种抗炎细胞因子。多种不同类型的产生IL-10，包括免疫细胞和非免疫细胞。IL-10树对突状细胞(DC)和巨噬细胞具有抑制作用，是呈递递的强效制剂，与Th1相关细胞因子IL-2和干扰素-γ(IFN-γ)的产生。IL-10也是感染期间的关键免疫调节剂，因为它能够抑制细胞因子的产生。因此，感染期间过度使用Th1和CD8+ T应答可能会受到抑制。
Tags：IL-10
Descriptions：LPS
Tags：LPS
Descriptions：Protein S100-A9, also known as S100 calcium binding protein A9, S100A9, and CAGB, is a member of the S-100 family. S100A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi.
Tags：S100A9
Descriptions：ICDHc
Tags：ICDHc
Descriptions：β-神经生长因子 (Beta-NGF) 是一种分子量为 27 kDa 的细胞因子，含有 241 个氨基酸残基。Beta-NGF 属于神经营养因子家族，具有神经营养因子的功能。它由 α、β、γ 亚基组成，其中 β 亚基与其生物活性相关。Beta-NGF 与 p75 神经营养因子受体和 Trk 受体结合，其功能分别与细胞死亡和存活相关。
Tags：β-NGF
Descriptions：Bone morphogenetic protein-2 (BMP-2) is a kind of bone growth regulator, belonging to protein transforming growth factor-β(TGF-β) superfamily. BMP-2 protein is involved in hedgehog pathway, TGF-β signaling pathway and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMP, which have been proved to be effective in inducing osteoblast differentiation in many cell types. The active form of BMP-2 can be composed of dimers of two identical proteins or heterodimers of two related bone morphogenetic proteins.
Tags：BMP-2
Descriptions：Mouse IL-10 is the prototypic member of the IL-10 cytokine family,including IL-10,IL-19,IL-20,IL-22(IL-TIF),IL-24 and IL-26.
Applications：No tag
Tags：IL-10
Descriptions：Polyamine Oxidase (PAO)
Descriptions：BAFF also known as BLYS, TALL-1 and TNFSF13B, which belongs to tumor necrosis factor family. BAFF is a 31.2 kDa type II transmembrane protein containing 285 residues that predominantly produced by myeloid cells, furthermore mouse BAFF shares 72% sequence identity with human BAFF. BAFF has been demonstrated to activate the survival of B cells and the B cell response by binding to BAFFR/BR3. Additionally, BAFF also takes part in regulating B and T cell function via forming two ligands-two receptors pathway through sharing TNFRSF13B/TACI and TNFRSF17/BCMA receptors with APRIL.
Tags：BAFF
