Descriptions：Mouse FGF1, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. It is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. Intracellular Mouse FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signalin.
Tags：FGF1
Descriptions：Soil Urease (S-UE)
Tags：Soil Urease (S-UE)
Descriptions：NiR
Tags：NiR
Descriptions：Bone morphogenetic protein -4 (BMP-4) is one of nine structurally related BMP's, belonging to transforming growth factor-β (TGF-β) superfamily, which secretes proteins. Mature BMP-4 is a dimer that binds to a multimeric transmembrane receptor with serine/threonine kinase activity. BMP-4 treatment promoted the proliferation of HCC cells and induced autophagy. Mechanism study shows that autophagy induced by BMP-4 is mediated by activating JNK1/Bcl2 pathway. JNK1 inhibitor and JNK1 knockout can weaken BMP-4-induced autophagy and eliminate BMP-4-promoted HCC cell growth. BMP-4 promotes the proliferation of HCC through autophagy activation of JNK1/Bcl-2 signaling.
Tags：BMP-4
Descriptions：细胞因子干扰素γ（IFN-γ）能够保护细胞免受病毒感染，属于干扰素家族。大量研究表明，抗原触发的细胞类型包括T细胞、幼稚CD4+T细胞、巨噬细胞、树突状细胞和B细胞。IFN-γ在触发巨噬细胞对抗多种微生物靶点方面发挥重要作用，并且是一种与抗增殖、促凋亡和抗肿瘤机制相关的多效性分子。由于IFN-γ被认为是免疫的主要效应因子，因此已被用于治疗多种疾病。
Tags：IFN-γ
Descriptions：Ethanol
Tags：Ethanol
Descriptions：白细胞介素17A（IL-17A）预测浓度为35 kDa，其编码基因IL17A是由活化T细胞产生的促炎细胞因子。该细胞因子调节剂NF-κB和丝裂原活化蛋白抑制剂的活性。
Tags：IL-17
Descriptions：ACP
Tags：ACP
Descriptions：Glucose Dehydrogenase (GCDH)
