Descriptions:Glutaminase (GLS)
Tags:Glutaminase (GLS)
Descriptions:细胞因子干扰素γ(IFN-γ)能够保护细胞免受病毒感染,属于干扰素家族。大量研究表明,抗原触发的细胞类型包括T细胞、幼稚CD4+T细胞、巨噬细胞、树突状细胞和B细胞。IFN-γ在触发巨噬细胞对抗多种微生物靶点方面发挥重要作用,并且是一种与抗增殖、促凋亡和抗肿瘤机制相关的多效性分子。由于IFN-γ被认为是免疫的主要效应因子,因此已被用于治疗多种疾病。
Tags:IFN-γ
Descriptions:Mouse FGF1, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. It is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. Intracellular Mouse FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signalin.
Tags:FGF1
Descriptions:白细胞介素-10 (IL-10),又称人类细胞因子合成抑制因子 (CSIF),是一种抗炎细胞因子。许多不同类型的细胞都能产生 IL-10,包括免疫细胞和非免疫细胞。IL-10 对树突状细胞 (DC) 和巨噬细胞具有抑制作用,是抗原呈递的强效抑制剂,并限制 Th1 相关细胞因子 IL-2 和干扰素-γ (IFN-γ) 的产生。IL-10 也是感染期间的关键免疫调节剂,因为它能够抑制炎症细胞因子的产生。因此,感染期间过度的 Th1 和 CD8+ T 细胞应答可能会受到抑制。
Tags:IL-10
Descriptions:Glucoamylase
Tags:Glucoamylase
Descriptions:Insulin like Growth Factors 1 (IGF-I) is a 7.79 kDa member of the Insulin-like Growth Factors with 71 amino acid residues. IGF-I is mainly expressed from liver, adipose tissue, Endometrial stromal cells, Leydig cells, and can be isolated from plasma. IGF-I mediating the protein anabolic and promoting effect of pituitary growth hormone. IGF-I also affects metabolism of glycogen, DNA synthesis and glucose uptake via binding to IGF-I receptor.
Tags:IGF-I
Descriptions:Total Sulfhydryl Group
Descriptions:Active matrix metalloproteinase-7 (Active MMP-7) is a 20.07 kDa matrix metalloproteinases with 180 amino acid residues. MMP-7 restricted production by normal mucosal and exocrine gland epithelial cells, as well as by carcinoma cells. Functionally, it involved breakdown of extracellular matrix (casein, gelatins of types I, III, IV, and V, and fibronectin) in normal physiological processes and disease processes. MMP-7 is contributed to early tumor development during carcinogenesis.
Tags:MMP7 (active)
Descriptions:白细胞介素-1β (IL-1β) 是一种在巨噬细胞、自然杀伤细胞、单核细胞和中性粒细胞中表达的主要细胞因子。它在反应中也发挥着重要作用,包括核单细胞活化剂,这对于后续的防御以及抵抗物资至关重要。IL-1β 前体被细胞浆骨髓天空白1 线粒体,形成成熟的IL-1β。
Tags:IL-1β
Descriptions:FBP
Tags:FBP