Descriptions：Glutaminase (GLS)
Tags：Glutaminase (GLS)
Descriptions：NR
Tags：NR
Descriptions：Bone morphogenetic protein -4 (BMP-4) is one of nine structurally related BMP's, belonging to transforming growth factor-β (TGF-β) superfamily, which secretes proteins. Mature BMP-4 is a dimer that binds to a multimeric transmembrane receptor with serine/threonine kinase activity. BMP-4 treatment promoted the proliferation of HCC cells and induced autophagy. Mechanism study shows that autophagy induced by BMP-4 is mediated by activating JNK1/Bcl2 pathway. JNK1 inhibitor and JNK1 knockout can weaken BMP-4-induced autophagy and eliminate BMP-4-promoted HCC cell growth. BMP-4 promotes the proliferation of HCC through autophagy activation of JNK1/Bcl-2 signaling.
Tags：BMP-4
Descriptions：Glucoamylase
Tags：Glucoamylase
Descriptions：细胞因子干扰素γ（IFN-γ）能够保护细胞免受病毒感染，属于干扰素家族。大量研究表明，抗原触发的细胞类型包括T细胞、幼稚CD4+T细胞、巨噬细胞、树突状细胞和B细胞。IFN-γ在触发巨噬细胞对抗多种微生物靶点方面发挥重要作用，并且是一种与抗增殖、促凋亡和抗肿瘤机制相关的多效性分子。由于IFN-γ被认为是免疫的主要效应因子，因此已被用于治疗多种疾病。
Tags：IFN-γ
Descriptions：Total Sulfhydryl Group
Descriptions：Malic enzyme (ME) is widely present in the cytoplasm of microorganisms, cultured cells, animals, and plants, especially with high activity in plant tissues. ME catalyzes the reversible oxidation decarboxylation of malic acid, producing pyruvate and CO2, as well as the reduction reaction accompanied by NAD(P)+, which is a key enzyme in malic acid metabolism.
Descriptions：Glucose Dehydrogenase (GCDH)
Descriptions：NiR
Tags：NiR
