Descriptions:Bone Morphogenetic Protein-7 (BMP-7) is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP7 can significantly inhibit TGF-β through binding with TGF-β receptor and trigger SMAD transcription factors, such as SMAD 1 /5/8. It plays a vital role in inhibiting the expansion of kidney damage and promoting the differentiation of osteoblasts.
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Tags:BMP-7
Descriptions:白细胞介素-17F(IL-17F)是一种与IL-17序列相似的细胞因子,IL-17最显著的作用是参与诱导和介导促炎反应。
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Tags:IL-17F
Descriptions:M-CSF is a potent hematopoietic factor produced by a variety of cells,including lymphocytes,monocytes,fibroblasts,endothelial cells,myoblasts and osteoblasts.
Applications:His tag
Tags:M-CSF
Descriptions:Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) is secreted by a number of different cell types (including activated T cells,Bcells,macrophages,mast cells,endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimulation.
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Tags:M-CSF
Descriptions:Transforming Growth Factors beta 2 (TGFβ-2) is a 12.85 kDa member of the epidermal Growth Factors with 113 amino acid residues. TGFβ-2 is expressed from throughout the body. TGFβ-2 is a regulator of cell proliferation, differentiation, apoptosis, cell plasticity and migration, etc. TGF-β-2 also associates with various kinds of diseases, such as cancer and tissue fibrosis.
Applications:His tag
Tags:TGF-β2
Descriptions:Interleukin 24 (IL-24) predicts a molecular mass of 18.2 kDa, is a cytokine belonging to the IL-10 family of cytokines that signals through IL-20R1 /IL-20R2 and IL-22R1 /IL-20R2. Its normal physiological role relates to wound healing, protection against diseases caused by bacteria.
Applications:His tag
Tags:IL-24
Descriptions:Bone Morphogenetic Protein-9 (BMP-9), known as Growth differentiation factor 2 (GDF2), is an extracellular multifunctional cytokine that is also a member of the TGF-β family. BMP-8B can bind with the TGF-β receptor and trigger SMAD protein signal transduction. BMP-9 is the most effective for the differentiation of osteoblasts in vivo, and the general BMP blocker does not affect it.
Applications:His tag
Tags:BMP-9
Descriptions:4-1BB ligand (4-1BBL) is a type II transmembrane protein that is part of the tumor necrosis factor (TNF) ligand family. As an inducible co-stimulatory molecule, it presents on several antigen presenting cell (APC) types, including B cells, macrophages and DCs. The interactions between 4-1BB and 4-1BBL trigger pleiotropic effects on the immune response including antigen presenting process, proliferation of CD4 and CD8 positive T-cells, as well as cytokine secretion from T-cells through NFκB, c-Jun, and p38 downstream signal pathways activation.Therefore, 4-1BB and 4-1BBL are recently used for the immunotherapy of cancer.
Applications:His tag
Tags:4-1BBL
Descriptions:C-X-C motif chemokine 6 (CXCL6) also named granulocyte chemotactic protein 2 (GCP-2), which is a chemokine of the intercrine alpha family. CXCL6 is a 8.3kDa protein containing 75 amino acid residues. CXCL6 has a significant role in resistance of gram-positive and gram-negative bacteria which is a chemotaxis for neutrophil granulocytes. CXCL6 has a role in in the process of carcinogenesis which affects proliferation and metastasis of OS cells by the interaction with CXCR1 /CXCR2.
Applications:His tag
Tags:CXCL6