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VWF Polyclonal Antibody

VWF Polyclonal Antibody

Views(2) Publications(0) Catalog no(ABP60910)
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Specification

Product name VWF Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human VWF protein
Host Rabbit
Reactivity Human,Rat,Mouse
Applications IHC,IF
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300;IF 1:50-200
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative von Willebrand factor; vWF

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 309kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background VWF gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.
Gene ID 7450
Alternative von Willebrand factor; vWF
Others The antibody detects endogenous levels of VWF protein
Accession P04275
Observed Band(KD) 309

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