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VAMP-1/2/3 Polyclonal Antibody

VAMP-1/2/3 Polyclonal Antibody

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Specification

Product name VAMP-1/2/3 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human VAMP-1/2/3
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1; VAMP2; SYB2; Vesicle-associated membrane protein 2; VAMP-2; Synaptobrevin-2; VAMP3; SYB3; Vesicle-associated membrane protein 3; VAMP-3; Cellubrevin; CEB; Synaptob

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Synapotobrevins, syntaxins, and the synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by VAMP1 (vesicle associated membrane protein 1) is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Mutations in VAMP1 are associated with autosomal dominant spastic ataxia 1. Multiple alternative splice variants have been described, but the full-length nature of some variants has not been defined.
Gene ID 6843/6844/9341
Alternative VAMP1; SYB1; Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1; VAMP2; SYB2; Vesicle-associated membrane protein 2; VAMP-2; Synaptobrevin-2; VAMP3; SYB3; Vesicle-associated membrane protein 3; VAMP-3; Cellubrevin; CEB; Synaptob
Others VAMP-1/2/3 Polyclonal Antibody detects endogenous levels of VAMP-1/2/3 protein.
Accession P23763/P63027/Q15836
Observed Band(KD) 13

Image & description

Fig. Western Blot analysis of Mouse-brain cells using VAMP-1/2/3 Polyclonal Antibody diluted at 1:1000. Secondary antibody was diluted at 1:20000.

Fig. Western Blot analysis of Mouse-brain cells using VAMP-1/2/3 Polyclonal Antibody diluted at 1:1000. Secondary antibody was diluted at 1:20000.

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