Product Information

• Product name

  TRPV4 Polyclonal Antibody

• Immunogen

  Synthesized peptide derived from the Internal region of human TRPV4

• Host

  Rabbit

• Reactivity

  Human, Mouse, Rat

• Applications

  ELISA, WB

• Application notes

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

• Clonality

  Polyclonal

• Isotype

  Rabbit IgG

• Purification

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Fig. Western Blot analysis of extracts from K562 cells, using TRPV4 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Product Properties

• Formulation

  Liquid solution

• Concentration

  1 mg/ml

• Storage buffer

  PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.

• Storage instructions

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Shipping

  Gel pack with blue ice.

• Precautions

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

• Background

  TRPV4 encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The transient receptor potential cation channel subfamily V member 4 is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene.

• Gene ID

  59341

• Alternative names

  TRPV4; VRL2; VROAC; Transient receptor potential cation channel subfamily V member 4; TrpV4; Osm-9-like TRP channel 4; OTRPC4; Transient receptor potential protein 12; TRP12; Vanilloid receptor-like channel 2; Vanilloid receptor-like protein 2; VRL-2; Vanilloid receptor-related osmotically-activated channel; VR-OAC

• Others

  TRPV4 Polyclonal Antibody detects endogenous levels of TRPV4 protein.

• Accession

  Q9HBA0