| Product name | Troponin I-C Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human Troponin I-C around the non-phosphorylation site of S43 |
| Host | Rabbit |
| Reactivity | Mouse,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 28kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: tnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
| Gene ID | 7137 |
| Alternative | TNNI3; TNNC1; Troponin I; cardiac muscle; Cardiac troponin I |
| Others | Troponin I-C Polyclonal Antibody detects endogenous levels of Troponin I-C protein. |
| Accession | P19429 |
| Observed Band(KD) | 28 |
Fig. Western Blot analysis of Mouse cells using Troponin I-C Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
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