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TRF1 (phospho Ser219) Polyclonal Antibody

TRF1 (phospho Ser219) Polyclonal Antibody

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Specification

Product name TRF1 (phospho Ser219) Polyclonal Antibody
Immunogen Synthesized peptide derived from human TRF1 around the phosphorylation site of S219
Host Rabbit
Reactivity Human, Mouse
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative TERF1; PIN2; TRBF1; TRF; TRF1; Telomeric repeat-binding factor 1; NIMA-interacting protein 2; TTAGGG repeat-binding factor 1; Telomeric protein Pin2/TRF1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background TERF1 (telomeric repeat binding factor 1) encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of TERF1 are alternatively spliced products.
Gene ID 7013
Alternative TERF1; PIN2; TRBF1; TRF; TRF1; Telomeric repeat-binding factor 1; NIMA-interacting protein 2; TTAGGG repeat-binding factor 1; Telomeric protein Pin2/TRF1
Others Phospho-TRF1 (S219) Polyclonal Antibody detects endogenous levels of TRF1 protein only when phosphorylated at S219.
Accession P54274
Observed Band(KD) 55

Image & description

Fig. Western Blot analysis of 293 cells using Phospho-TRF1 (S219) Polyclonal Antibody.

Fig. Western Blot analysis of 293 cells using Phospho-TRF1 (S219) Polyclonal Antibody.

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