| Product name | TOP1M Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human TOP1M protein |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | DNA topoisomerase I, mitochondriall; TOP1mt |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 66kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | TOP1MT (DNA Topoisomerase I Mitochondrial) is a Protein Coding gene. TOP1MT encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed forTOP1MT. |
| Gene ID | 116447 |
| Alternative | DNA topoisomerase I, mitochondriall; TOP1mt |
| Others | The antibody detects endogenous levels of TOP1M protein |
| Accession | Q969P6 |
| Observed Band(KD) | 66 |
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