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TNIP3 Polyclonal Antibody

TNIP3 Polyclonal Antibody

Views(3) Publications(0) Catalog no(ABP60717)
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Specification

Product name TNIP3 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human TNIP3 protein at amino acid sequence of 40-120
Host Rabbit
Reactivity Human
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative TNFAIP3-interacting protein 3; A20-binding inhibitor of NF-kappa-B activation 3; ABIN-3; Listeria-induced gene protein

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 35kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background TNIP3 (TNFAIP3 Interacting Protein 3) is a Protein Coding gene. Among its related pathways are Ovarian tumor domain proteases and Immune response IL-23 signaling pathway. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
Gene ID 79931
Alternative TNFAIP3-interacting protein 3; A20-binding inhibitor of NF-kappa-B activation 3; ABIN-3; Listeria-induced gene protein
Others The antibody detects endogenous levels of TNIP3 protein
Accession Q96KP6
Observed Band(KD) 35

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