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TERF2 Polyclonal Antibody

TERF2 Polyclonal Antibody

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Specification

Product name TERF2 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human TERF2 protein at amino acid sequence of 130-210
Host Rabbit
Reactivity Human,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Telomeric repeat-binding factor 2 ; TTAGGG repeat-binding factor 2; Telomeric DNA-binding protein

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 55kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background TERF2 encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.
Gene ID 7014
Alternative Telomeric repeat-binding factor 2 ; TTAGGG repeat-binding factor 2; Telomeric DNA-binding protein
Others The antibody detects endogenous levels of TERF2 protein
Accession Q15554
Observed Band(KD) 55

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