| Product name | SPTN4 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human SPTN4 protein |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC,IF |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Spectrin beta chain, non-erythrocytic 4; Beta-IV spectrin; Spectrin, non-erythroid beta chain 3 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 282kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. SPTBN4 is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for SPTBN4. |
| Gene ID | 57731 |
| Alternative | Spectrin beta chain, non-erythrocytic 4; Beta-IV spectrin; Spectrin, non-erythroid beta chain 3 |
| Others | The antibody detects endogenous levels of SPTN4 protein |
| Accession | Q9H254 |
| Observed Band(KD) | 282 |
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