| Product name | Sp1 (phospho Thr739) Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from human Sp1 around the phosphorylation site of T739 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat,Monkey |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | SP1; TSFP1; Transcription factor Sp1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 81kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Sp1 transcription factor encoded by Sp1 transcription factor is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. Sp1 transcription factor is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of Sp1 transcription factor, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for Sp1. |
| Gene ID | 6667 |
| Alternative | SP1; TSFP1; Transcription factor Sp1 |
| Others | Phospho-Sp1 (T739) Polyclonal Antibody detects endogenous levels of Sp1 protein only when phosphorylated at T739. |
| Accession | P08047 |
| Observed Band(KD) | 81 |
Fig. Western Blot analysis of various cells using Phospho-Sp1 (T739) Polyclonal Antibody diluted at 1:1000.
Author：L Xing, CX Yang, D Zhao Publication name：Journal of Controlled Release IF：8.044
Author：Zhang S.-B, Liu T.-J, et al. Publication name：Cellular Physiology and Biochemistry. IF：4.81
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