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SGK1 Mouse Monoclonal Antibody (4D12)

SGK1 Mouse Monoclonal Antibody (4D12)

Views(42) Publications(0) Catalog no(ABM40269)
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Specification

Product name SGK1 Mouse Monoclonal Antibody (4D12)
Immunogen Synthetic Peptide of SGK1 at AA range of 350-430
Host Mouse
Reactivity Human, Mouse, Rat
Applications IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).
Clonality Monoclonal
Preparation method The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
Alternative SGK1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background SGK1 (serum/glucocorticoid regulated kinase 1) encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for SGK1.
Gene ID 6446
Alternative SGK1
Others SGK1 protein detects endogenous levels of SGK1.
Accession O00141
Observed Band(KD) 45-60

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using SGK1 Mouse mAb diluted at 1:200.

Fig.1. Immunohistochemical analysis of paraffin-embedded Human Brain Tissue using SGK1 Mouse mAb diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human Kidney Carcinoma Tissue using SGK1 Mouse mAb diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded Human Kidney Carcinoma Tissue using SGK1 Mouse mAb diluted at 1:200.

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