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RHCE Polyclonal Antibody

RHCE Polyclonal Antibody

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Specification

Product name RHCE Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human RHCE protein at amino acid sequence of 161-210
Host Rabbit
Reactivity Human
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Blood group Rh(CE) polypeptide; Rh polypeptide 1; RhPI; Rh30A; RhIXB; Rhesus C/E antigens; CD_antigen: CD240CE

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 45kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in RHCE results in amorph-type Rh- disease. Alternative splicing of RHCE results in multiple transcript variants encoding several different isoforms.
Gene ID 6006
Alternative Blood group Rh(CE) polypeptide; Rh polypeptide 1; RhPI; Rh30A; RhIXB; Rhesus C/E antigens; CD_antigen: CD240CE
Others The antibody detects endogenous levels of RHCE protein
Accession P18577
Observed Band(KD) 45

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