| Product name | RB6I2 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human RB6I2 protein |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | ELKS/Rab6-interacting/CAST family member 1; ERC-1; Rab6-interacting protein 2 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 122kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The protein encoded by ERC1 (ELKS/RAB6-Interacting/CAST Family Member 1) is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. ERC1 is a Protein Coding gene. Diseases associated with ERC1 include Differentiated Thyroid Carcinoma and Distal Monosomy 12P. Among its related pathways are NF-kappa B signaling pathway and Cytoskeletal Signaling. |
| Gene ID | 23085 |
| Alternative | ELKS/Rab6-interacting/CAST family member 1; ERC-1; Rab6-interacting protein 2 |
| Others | The antibody detects endogenous levels of RB6I2 protein |
| Accession | Q8IUD2 |
| Observed Band(KD) | 122 |
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