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RAGE Polyclonal Antibody

RAGE Polyclonal Antibody

Views(55) Publications(0) Catalog no(ABP54014)
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Specification

Product name RAGE Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human RAGE at AA range: 133-182
Host Rabbit
Reactivity Human
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative AGER; RAGE; Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The advanced glycosylation end product (AGE) receptor encoded by AGER is a member of the immunoglobulin superfamily of cell surface receptors. It is a multiligand receptor, and besides AGE, interacts with other molecules implicated in homeostasis, development, and inflammation, and certain diseases, such as diabetes and Alzheimer's disease. Many alternatively spliced transcript variants encoding different isoforms, as well as non-protein-coding variants, have been described for this gene (PMID: 18089847).
Gene ID 177
Alternative AGER; RAGE; Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products
Others RAGE Polyclonal Antibody detects endogenous levels of RAGE protein.
Accession Q15109
Observed Band(KD) 37

Image & description

Fig. Western Blot analysis of 3T3 cells using RAGE Polyclonal Antibody diluted at 1:1000.

Fig. Western Blot analysis of 3T3 cells using RAGE Polyclonal Antibody diluted at 1:1000.

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