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PMS1 Polyclonal Antibody

PMS1 Polyclonal Antibody

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Specification

Product name PMS1 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human PMS1 at AA range: 410-490
Host Rabbit
Reactivity Human
Applications ELISA, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative PMS1; PMSL1; PMS1 protein homolog 1; DNA mismatch repair protein PMS1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background PMS1 encodes a protein belonging to the DNA mismatch repair mutL/hexB family. PMS1 homolog 1, mismatch repair system component is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
Gene ID 5378
Alternative PMS1; PMSL1; PMS1 protein homolog 1; DNA mismatch repair protein PMS1
Others PMS1 Polyclonal Antibody detects endogenous levels of PMS1 protein.
Accession P54277
Observed Band(KD) 105

Image & description

Fig.1. Western Blot analysis of various cells using PMS1 Polyclonal Antibody.

Fig.1. Western Blot analysis of various cells using PMS1 Polyclonal Antibody.

Fig.2. Western Blot analysis of Jurkat cells using PMS1 Polyclonal Antibody.

Fig.2. Western Blot analysis of Jurkat cells using PMS1 Polyclonal Antibody.

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