| Product name | PIAS 3 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the N-terminal region of human PIAS 3 at AA range: 10-90 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | PIAS3; E3 SUMO-protein ligase PIAS3; Protein inhibitor of activated STAT protein 3 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 68kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | PIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of PIAS3 have been identified, but the full-length nature of some of these variants has not been determined. |
| Gene ID | 10401 |
| Alternative | PIAS3; E3 SUMO-protein ligase PIAS3; Protein inhibitor of activated STAT protein 3 |
| Others | PIAS 3 Polyclonal Antibody detects endogenous levels of PIAS 3 protein. |
| Accession | Q9Y6X2 |
| Observed Band(KD) | 68 |
Fig.1. Western Blot analysis of various cells using PIAS 3 Polyclonal Antibody diluted at 1:2000.
Fig.2. Western Blot analysis of 293 cells using PIAS 3 Polyclonal Antibody diluted at 1:2000.
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