| Product name | PACS1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human PACS1 protein at amino acid sequence of 400-480 |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Phosphofurin acidic cluster sorting protein 1; PACS-1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 105kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | PACS1 (Phosphofurin Acidic Cluster Sorting Protein 1) encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. |
| Gene ID | 55690 |
| Alternative | Phosphofurin acidic cluster sorting protein 1; PACS-1 |
| Others | The antibody detects endogenous levels of PACS1 protein |
| Accession | Q6VY07 |
| Observed Band(KD) | 105 |
You must be logged in to post a review.
Reviews
There are no reviews yet.