| Product name | P2X3 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human P2X3 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 44kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The product of P2RX3 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. |
| Gene ID | 5024 |
| Alternative | P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor |
| Others | P2X3 Polyclonal Antibody detects endogenous levels of P2X3 protein. |
| Accession | P56373 |
| Observed Band(KD) | 44 |
Fig.1. Western Blot analysis of K562 cells using P2X3 Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
Fig.2. Immunohistochemical analysis of paraffin-embedded human-heart, antibody was diluted at 1:100.
Fig.3. Immunohistochemical analysis of paraffin-embedded human-heart, antibody was diluted at 1:100.
Fig.4. Immunohistochemical analysis of paraffin-embedded Mouse-heart, antibody was diluted at 1:100.
Fig.5. Immunohistochemical analysis of paraffin-embedded Mouse-heart, antibody was diluted at 1:100.
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