| Product name | OPA1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human OPA1 protein |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000). |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen |
| Alternative | Dynamin-like 120 kDa protein, mitochondrial; Optic atrophy protein 1 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Storage buffer | PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | The protein encoded by OPA1 gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. |
| Gene ID | 4976 |
| Alternative | Dynamin-like 120 kDa protein, mitochondrial; Optic atrophy protein 1 |
| Others | The antibody detects endogenous levels of OPA1 protein |
| Accession | O60313 |
| Observed Band(KD) | 105 |
Author：Jia, Lina, et al. Publication name：Ecotoxicology and Environmental Safety IF：6.8
You must be logged in to post a review.
1.The species of antibody reactivity should be the sample species that can be matched normally after Abbkine R&D experts have passed strict scientific verification. If your sample is not within the range of reactivity, in order to improve the efficiency and results of your experiment, it is not suggested to try other species. Otherwise, it may lead to sample mismatch and affect the effect of your experiment.
2.Please aliquot the antibody received as soon as possible and store it at -20℃, avoid repeated freezing and thawing, and use it within one year.
Welcome any form of communications, and better service will be provided here.
Tell： +1-404-854-0155
Email： service@abbkine.com
Address： 3052 Stroop Hill Road, Apt 203, Atlanta 30303, Georgia, United States of America
Reviews
There are no reviews yet.