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OBCAM Polyclonal Antibody

OBCAM Polyclonal Antibody

Views(16) Publications(0) Catalog no(ABP51997)
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Specification

Product name OBCAM Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human OBCAM
Host Rabbit
Reactivity Human, Monkey, Mouse, Rat
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative OPCML; IGLON1; OBCAM; Opioid-binding protein/cell adhesion molecule; OBCAM; OPCML; Opioid-binding cell adhesion molecule; IgLON family member 1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background OPCML encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. Opioid binding protein/cell adhesion molecule like is proteolytically processed to generate the mature protein. Opioid binding protein/cell adhesion molecule like is localized in the plasma membrane and may have an accessory role in opioid receptor function. OPCML has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the opioid binding protein/cell adhesion molecule like is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Gene ID 4978
Alternative OPCML; IGLON1; OBCAM; Opioid-binding protein/cell adhesion molecule; OBCAM; OPCML; Opioid-binding cell adhesion molecule; IgLON family member 1
Others OBCAM Polyclonal Antibody detects endogenous levels of OBCAM protein.
Accession Q14982
Observed Band(KD) 58

Image & description

Fig. Western Blot analysis of various cells using OBCAM Polyclonal Antibody diluted at 1:1000.

Fig. Western Blot analysis of various cells using OBCAM Polyclonal Antibody diluted at 1:1000.

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