| Product name | NTE Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from the Internal region of human NTE |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Applications | WB,IHC,IF,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | PNPLA6; NTE; Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6 |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 150kD |
| Storage buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | PNPLA6 encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Gene ID | 10908 |
| Alternative | PNPLA6; NTE; Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6 |
| Others | NTE Polyclonal Antibody detects endogenous levels of NTE protein. |
| Accession | Q8IY17 |
| Observed Band(KD) | 150 |
Fig.1. Western Blot analysis of AD293 cells using NTE Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.
Fig.2. Immunohistochemical analysis of paraffin-embedded rat-testis, antibody was diluted at 1:100.
Fig.3. Immunohistochemical analysis of paraffin-embedded rat-testis, antibody was diluted at 1:100.
Fig.4. Immunohistochemical analysis of paraffin-embedded rat-testis, antibody was diluted at 1:100.
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