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NT-3 Polyclonal Antibody

NT-3 Polyclonal Antibody

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Specification

Product name NT-3 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human NT-3 protein at amino acid sequence of 180-230
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Alternative Neurotrophin-3; NT-3; HDNF; Nerve growth factor 2; NGF-2; Neurotrophic factor

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol as stabilizer.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by NTF3 is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. NTF3 (Neurotrophin 3) is a Protein Coding gene. Diseases associated with NTF3 include Hypochondriasis and Diabetic Polyneuropathy. Among its related pathways are p70S6K Signaling and Akt Signaling.
Gene ID 4908
Alternative Neurotrophin-3; NT-3; HDNF; Nerve growth factor 2; NGF-2; Neurotrophic factor
Others The antibody detects endogenous levels of NT-3
Accession P20783

Image & description

Fig.1. Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200.

Fig.1. Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

Fig.2. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200.

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