| Product name | NRCAM Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human NRCAM protein at amino acid sequence of 1050-1130 |
| Host | Rabbit |
| Reactivity | Human,Rat,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Neuronal cell adhesion molecule; Neuronal surface protein Bravo; NgCAM-related cell adhesion molecule; Ng-CAM-related |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 143kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. NRCAM encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. NRCAM is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of NRCAM have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Gene ID | 4897 |
| Alternative | Neuronal cell adhesion molecule; Neuronal surface protein Bravo; NgCAM-related cell adhesion molecule; Ng-CAM-related |
| Others | The antibody detects endogenous levels of NRCAM protein |
| Accession | Q92823 |
| Observed Band(KD) | 143 |
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