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NQO2 Polyclonal Antibody

NQO2 Polyclonal Antibody

Views(4) Publications(0) Catalog no(ABP59518)
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Specification

Product name NQO2 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human NQO2 protein at amino acid sequence of 40-120
Host Rabbit
Reactivity Human,Rat,Mouse
Applications WB,ELISA
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Alternative Ribosyldihydronicotinamide dehydrogenase [quinone]; NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Molecular weight 25kD
Storage buffer PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background NQO2 (N-Ribosyldihydronicotinamide: quinone Reductase 2) is a Protein Coding gene. Among its related pathways are Metabolism and Cytochrome P450 - arranged by substrate type. NQO2 encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in NQO2 have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants.
Gene ID 4835
Alternative Ribosyldihydronicotinamide dehydrogenase [quinone]; NRH dehydrogenase [quinone] 2; NRH:quinone oxidoreductase 2; Quinone reductase 2; QR2
Others The antibody detects endogenous levels of NQO2 protein
Accession P16083
Observed Band(KD) 25

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