Login Register
English
0

Cart

$ 0

Nephrin Polyclonal Antibody

Nephrin Polyclonal Antibody

Views(134) Publications(0) Catalog no(ABP55412)
Datasheet Print Share Email Share
  • Specification
  • FAQ
  • Publications(0)
  • Comments(0)

Specification

Product name Nephrin Polyclonal Antibody
Immunogen Synthesized peptide derived from the C-terminal region of human Nephrin
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IHC-P
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative NPHS1; NPHN; Nephrin; Renal glomerulus-specific cell adhesion receptor

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background NPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
Gene ID 4868
Alternative NPHS1; NPHN; Nephrin; Renal glomerulus-specific cell adhesion receptor
Others Nephrin Polyclonal Antibody detects endogenous levels of Nephrin protein.
Accession O60500

Image & description

This product has been cited in0publications

Reviews

There are no reviews yet.

Be the first to review “Nephrin Polyclonal Antibody”