Login Register
English
0

Cart

$ 0

NACA Polyclonal Antibody

NACA Polyclonal Antibody

Views(210) Publications(0) Catalog no(ABP59394)
Datasheet Print Share Email Share
  • Specification
  • FAQ
  • Publications(0)
  • Comments(0)

Specification

Product name NACA Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human NACA protein at amino acid sequence of 100-180
Host Rabbit
Reactivity Human, Mouse
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Alternative Nascent polypeptide-associated complex subunit alpha; NAC-alpha; Alpha-NAC; Hom s 2; NACA; HSD48

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background NACA encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of NACA on different chromosomes.
Gene ID 4666
Alternative Nascent polypeptide-associated complex subunit alpha; NAC-alpha; Alpha-NAC; Hom s 2; NACA; HSD48
Others The antibody detects endogenous levels of NACA protein
Accession Q13765
Observed Band(KD) 23

Image & description

This product has been cited in0publications

Reviews

There are no reviews yet.

Be the first to review “NACA Polyclonal Antibody”