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MYL2 Polyclonal Antibody

MYL2 Polyclonal Antibody

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Specification

Product name MYL2 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human MYL2 protein at amino acid sequence of 91-140
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Alternative Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; MLC-2; MLC-2v

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol as stabilizer.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background MYL2 (Myosin Light Chain 2) is a Protein Coding gene. Diseases associated with MYL2 include Cardiomyopathy, Hypertrophic, 10 and Congenital Fiber-Type Disproportion. Among its related pathways are Focal Adhesion and Sertoli-Sertoli Cell Junction Dynamics. Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Gene ID 4633
Alternative Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; MLC-2; MLC-2v
Others The antibody detects endogenous levels of MYL2
Accession P10916
Observed Band(KD) 18

Image & description

Fig.1. Western Blot analysis of 1, Mouse-heart 2, Hela cells using primary antibody diluted at 1:500 (4°C overnight). Goat Anti-rabbit IgG Dylight 800 (Cat #: A23920) secondary antibody was diluted at 1:5000 at 25°C for 1 hour.

Fig.1. Western Blot analysis of 1, Mouse-heart 2, Hela cells using primary antibody diluted at 1:500 (4°C overnight). Goat Anti-rabbit IgG Dylight 800 (Cat #: A23920) secondary antibody was diluted at 1:5000 at 25°C for 1 hour.

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