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MRP1 Polyclonal Antibody

MRP1 Polyclonal Antibody

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Product name MRP1 Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human MRP1 protein at amino acid sequence of 110-190
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Alternative Multidrug resistance-associated protein 1; Leukotriene C(4) transporter; LTC4 transporter; ATP-binding cassette sub-family C member 1

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background ABCC1 (ATP Binding Cassette Subfamily C Member 1) is a Protein Coding gene. Diseases associated with ABCC1 include Dubin-Johnson Syndrome and Microsporidiosis. Among its related pathways are Doxorubicin Pathway, Pharmacokinetics and CDK-mediated phosphorylation and removal of Cdc6. The protein encoded by ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.
Gene ID 4363
Alternative Multidrug resistance-associated protein 1; Leukotriene C(4) transporter; LTC4 transporter; ATP-binding cassette sub-family C member 1
Others The antibody detects endogenous levels of MRP1 protein
Accession P33527
Observed Band(KD) 168

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