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MRG15 Polyclonal Antibody

MRG15 Polyclonal Antibody

Views(50) Publications(0) Catalog no(ABP53573)
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Specification

Product name MRG15 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human MRG15 at AA rangle: 1-80
Host Rabbit
Reactivity Human, Mouse
Applications ELISA, IF, IHC-P, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative MORF4L1; MRG15; FWP006; HSPC008; HSPC061; PP368; Mortality factor 4-like protein 1; MORF-related gene 15 protein; Protein MSL3-1; Transcription factor-like protein MRG15

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.
Gene ID 10933
Alternative MORF4L1; MRG15; FWP006; HSPC008; HSPC061; PP368; Mortality factor 4-like protein 1; MORF-related gene 15 protein; Protein MSL3-1; Transcription factor-like protein MRG15
Others MRG15 Polyclonal Antibody detects endogenous levels of MRG15 protein.
Accession Q9UBU8
Observed Band(KD) 41

Image & description

Fig.1. Western Blot analysis of Mouse cells using MRG15 Polyclonal Antibody diluted at 1:500.

Fig.1. Western Blot analysis of Mouse cells using MRG15 Polyclonal Antibody diluted at 1:500.

Fig.2. Western blot analysis of Mouse-kidney Mouse-brain lysis using MRG15 antibody. Antibody was diluted at 1:500.

Fig.2. Western blot analysis of Mouse-kidney Mouse-brain lysis using MRG15 antibody. Antibody was diluted at 1:500.

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