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MEL-1A-R Polyclonal Antibody

MEL-1A-R Polyclonal Antibody

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Specification

Product name MEL-1A-R Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human MEL-1A-R at AA range: 160-240
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IF
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background MTNR1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Gene ID 4543
Alternative MTNR1A; Melatonin receptor type 1A; Mel-1A-R; Mel1a receptor
Others MEL-1A-R Polyclonal Antibody detects endogenous levels of MEL-1A-R protein.
Accession P48039

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