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MARCO Polyclonal Antibody

MARCO Polyclonal Antibody

Views(244) Publications(0) Catalog no(ABP59218)
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Specification

Product name MARCO Polyclonal Antibody
Immunogen Synthesized peptide derived from part region of human MARCO protein at amino acid sequence of 380-460
Host Rabbit
Reactivity Human, Mouse
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
Alternative Macrophage receptor MARCO; Macrophage receptor with collagenous structure; Scavenger receptor class A member 2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The protein encoded by MARCO (Macrophage Receptor With Collagenous Structure) is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
Gene ID 8685
Alternative Macrophage receptor MARCO; Macrophage receptor with collagenous structure; Scavenger receptor class A member 2
Others The antibody detects endogenous levels of MARCO protein
Accession Q9UEW3
Observed Band(KD) 57

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