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mAChR M2 Polyclonal Antibody

mAChR M2 Polyclonal Antibody

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Specification

Product name mAChR M2 Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human mAChR M2 at AA rangle: 160-240
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, IF, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative CHRM2; Muscarinic acetylcholine receptor M2

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.
Gene ID 1129
Alternative CHRM2; Muscarinic acetylcholine receptor M2
Others mAChR M2 Polyclonal Antibody detects endogenous levels of mAChR M2 protein.
Accession P08172
Observed Band(KD) 85

Image & description

Fig. Western Blot analysis of HeLa cells using mAChR M2 Polyclonal Antibody.

Fig. Western Blot analysis of HeLa cells using mAChR M2 Polyclonal Antibody.

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