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M6A Polyclonal Antibody

M6A Polyclonal Antibody

Views(30) Publications(0) Catalog no(ABP52775)
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Specification

Product name M6A Polyclonal Antibody
Immunogen Synthesized peptide derived from the Internal region of human M6A at AA range: 140-220
Host Rabbit
Reactivity Human, Mouse, Rat
Applications ELISA, WB
Applications notes Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
Clonality Polyclonal
Preparation method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Alternative GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a

Product Properties

Formulation Liquid solution
Concentration 1 mg/ml
Storage buffer PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage instructions Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Gel pack with blue ice.
Precautions The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Additional Information

Background GPM6A (Glycoprotein M6A) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include calcium channel activity. An important paralog of this gene is PLP1. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
Gene ID 2823
Alternative GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a
Others M6A Polyclonal Antibody detects endogenous levels of M6A protein.
Accession P51674
Observed Band(KD) 31

Image & description

Fig. Western Blot analysis of extracts from rat stomach, using M6A Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

Fig. Western Blot analysis of extracts from rat stomach, using M6A Polyclonal Antibody. Secondary antibody (catalog#: A21020) was diluted at 1:20000.

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