| Product name | LSM1 Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human LSM1 protein at amino acid sequence of 50-130 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | WB,ELISA |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000;ELISA 1:5000-20000 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | U6 snRNA-associated Sm-like protein LSm1; Cancer-associated Sm-like; Small nuclear ribonuclear CaSm |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 14kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | LSM1 encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of LSM1 may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for LSM1, and a pseudogene of LSM1 is located on the short arm of chromosome 9. |
| Gene ID | 27257 |
| Alternative | U6 snRNA-associated Sm-like protein LSm1; Cancer-associated Sm-like; Small nuclear ribonuclear CaSm |
| Others | The antibody detects endogenous levels of LSM1 protein |
| Accession | O15116 |
| Observed Band(KD) | 14 |
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