| Product name | LRP1B Polyclonal Antibody |
| Immunogen | Synthesized peptide derived from part region of human LRP1B protein at amino acid sequence of 200-280 |
| Host | Rabbit |
| Reactivity | Human,Mouse |
| Applications | IHC,IF |
| Applications notes | Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300;IF 1:50-200 |
| Clonality | Polyclonal |
| Preparation method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Alternative | Low-density lipoprotein receptor-related protein 1B; LRP-1B; Low-density lipoprotein receptor-related protein-deleted in tumor; LRP-DIT |
| Formulation | Liquid solution |
| Concentration | 1 mg/ml |
| Molecular weight | 505kD |
| Storage buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Storage instructions | Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Shipping | Gel pack with blue ice. |
| Precautions | The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product. |
| Background | LRP1B is a putative tumor suppressor and a member of the low-density lipoprotein (LDL) receptor family. The LDL receptor family have roles related to clearance of extracellular ligand and are proposed to be involved in extracellular signal transduction. silencing and down-expression of LRP1B as been observed in renal cell carcinoma and thyroid cancer. Further Deletion of LRP1B has been associated with chemotherapy resistance in high-grade serous cancers. |
| Gene ID | 53353 |
| Alternative | Low-density lipoprotein receptor-related protein 1B; LRP-1B; Low-density lipoprotein receptor-related protein-deleted in tumor; LRP-DIT |
| Others | The antibody detects endogenous levels of LRP1B protein |
| Accession | Q9NZR2 |
| Observed Band(KD) | 505 |
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